A recent study conducted by researchers from Hebrew University-Hadassah Medical Center suggests that mushroom extract containing psilocybin may offer more potent and enduring effects on synaptic plasticity compared to chemically synthesised psilocybin. This research indicates potential therapeutic benefits for psychiatric disorders, addressing the inadequacy of current medications for conditions like depression, OCD, and schizophrenia. The study highlights the differences in synaptic protein levels and metabolomic profiles between the mushroom extract and synthetic psilocybin, hinting at the extract's unique influence on oxidative stress and energy production pathways. Despite historical preferences for isolated compounds in Western medicine, the study emphasises the potential of natural extracts, particularly from mushrooms, due to controlled cultivation methods enabling consistent production. This research not only underscores the superiority of extracts but also suggests their feasibility for incorporation into Western medicine.

Read more: https://neurosciencenews.com/psilocybin-mental-health-25739/

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March 27, 2024

Mushroom Extract Outperforms Synthetic Psilocybin in Psychiatric Therapy